Stem Cell Therapy at Cleveland Clinic

Stem Cell Therapy provides specialized treatment using blood-forming stem cells to restore or replace damaged or diseased blood-forming tissues in selected medical conditions. In cancer care, stem cell transplantation may be used for certain blood cancers and disorders and can involve the patient's own stem cells or cells obtained from a suitable donor. Treatment is individualized based on the underlying disease, previous therapy, overall health and transplant requirements.

Price

Price on Request

Why Price on Request?

The cost of stem cell therapy depends on the underlying disease, type of stem cell treatment, stem cell collection, donor requirements, conditioning therapy, hospitalization, medications, laboratory testing, transplantation and follow-up care required. A personalized estimate is provided according to the patient's treatment plan.

Complete Description

What Is Stem Cell Therapy?

Stem Cell Therapy uses blood-forming stem cells as part of treatment for selected diseases affecting the blood, bone marrow and immune system.

In oncology and hematology, stem cell therapy may be performed as a stem cell transplant after appropriate conditioning treatment.

Who May Need Stem Cell Therapy?

Stem cell therapy may be considered for selected patients with:

• Leukemia

• Lymphoma

• Multiple myeloma

• Myelodysplastic syndromes

• Selected bone marrow disorders

• Certain blood-related diseases

• Other conditions requiring stem cell replacement

Stem Cell Therapy Consultation

A specialist consultation may include:

• Detailed medical history

• Disease history

• Physical examination

• Laboratory testing

• Bone marrow evaluation

• Imaging when appropriate

• Previous treatment review

• Assessment of treatment suitability

Stem Cell Therapy Evaluation

Before treatment, specialists may evaluate:

• Underlying disease

• Disease status

• Previous treatments

• Blood counts

• Bone marrow function

• Kidney function

• Liver function

• Heart and lung health

• Infection status

• Overall fitness for treatment

Autologous Stem Cell Therapy

Autologous stem cell therapy uses the patient's own stem cells.

The stem cells are collected before high-dose treatment and stored until they are needed for reinfusion.

This approach may be used for selected cancers, including certain cases of multiple myeloma and lymphoma.

Allogeneic Stem Cell Therapy

Allogeneic stem cell therapy uses stem cells from another person.

A suitable donor may be identified through:

• Family matching

• Unrelated donor matching

• Other appropriate donor sources

Donor compatibility is assessed before transplantation.

Stem Cell Collection

Stem cells can be collected from the bloodstream using a specialized procedure.

The process may involve:

• Preparation of the patient or donor

• Stem cell mobilization when appropriate

• Blood collection

• Stem cell separation

• Cell processing and storage

Stem Cell Mobilization

For autologous transplantation, medicines may sometimes be used to encourage stem cells to move from the bone marrow into the bloodstream before collection.

Stem Cell Processing and Storage

After collection, stem cells may be processed and stored under controlled conditions until they are ready for transplantation.

Conditioning Treatment

Before stem cell infusion, selected patients receive conditioning treatment.

This may include:

• High-dose chemotherapy

• Radiation therapy

• Other conditioning medicines

The purpose depends on the disease and type of transplant.

Stem Cell Infusion

After conditioning, collected stem cells are infused into the bloodstream.

The transplanted cells can travel to the bone marrow and begin producing new blood cells.

Stem Cell Engraftment

Engraftment occurs when transplanted stem cells begin producing healthy blood cells.

During this period, patients may require close monitoring and supportive treatment.

Stem Cell Therapy for Leukemia

Selected patients with leukemia may undergo stem cell transplantation.

Treatment selection depends on:

• Leukemia subtype

• Disease status

• Genetic characteristics

• Previous treatments

• Overall health

• Donor availability

Stem Cell Therapy for Lymphoma

Selected patients with lymphoma may receive autologous or allogeneic stem cell transplantation depending on the disease and treatment history.

Stem Cell Therapy for Multiple Myeloma

Autologous stem cell transplantation may be used for selected patients with multiple myeloma as part of a broader treatment plan.

Stem Cell Therapy for Bone Marrow Disorders

Certain bone marrow disorders may be treated with stem cell transplantation when appropriate.

Treatment decisions depend on disease characteristics, patient health and available treatment options.

Stem Cell Therapy for Blood Disorders

Selected non-cancerous blood or bone marrow disorders may also be evaluated for stem cell transplantation when clinically appropriate.

Stem Cell Therapy Monitoring

Patients may require close monitoring during and after treatment.

Monitoring may include:

• Blood counts

• Organ function

• Infection status

• Disease response

• Stem cell engraftment

• Treatment-related complications

Infection Prevention

After conditioning and transplantation, immune function may be reduced.

Care may include:

• Infection monitoring

• Preventive medications

• Laboratory testing

• Early treatment of infections

• Appropriate protective measures

Blood Transfusion Support

Patients may require supportive transfusions during the period when blood counts are low.

Support may include:

• Red blood cells

• Platelets

• Other clinically appropriate blood products

Graft-Versus-Host Disease

Patients receiving allogeneic stem cells may develop graft-versus-host disease, in which donor immune cells react against the recipient's tissues.

Transplant teams monitor for this complication and provide treatment when necessary.

Stem Cell Therapy Recovery

Recovery varies depending on:

• Type of transplant

• Underlying disease

• Conditioning treatment

• Complications

• Immune recovery

• Overall health

Patients may require regular medical follow-up during recovery.

Long-Term Follow-Up

Long-term follow-up may include:

• Blood tests

• Bone marrow evaluation

• Disease surveillance

• Infection monitoring

• Immune recovery assessment

• Organ function monitoring

Stem Cell Therapy Second Opinion

Patients who have received a recommendation for stem cell therapy may seek a stem cell transplant second opinion.

Specialists may review:

• Disease diagnosis

• Bone marrow results

• Genetic testing

• Previous treatments

• Transplant indication

• Donor information

• Proposed treatment plan

International Patients

International patients should provide comprehensive medical records whenever possible.

Useful documents may include:

• Bone marrow biopsy reports

• Pathology reports

• Genetic and molecular testing

• Blood test results

• Imaging studies

• Previous chemotherapy records

• Previous radiation records

• Stem cell collection records

• Transplant evaluations

• Current medication list

Benefits of Specialized Stem Cell Therapy

Specialized stem cell therapy may help:

• Evaluate transplant eligibility

• Treat selected blood cancers

• Replace damaged blood-forming cells

• Provide autologous transplantation

• Provide allogeneic transplantation

• Coordinate stem cell collection

• Support stem cell engraftment

• Monitor transplant recovery

• Manage transplant complications

• Provide long-term follow-up

Why Choose Cleveland Clinic for Stem Cell Therapy?

Cleveland Clinic provides multidisciplinary hematology, oncology and transplant care involving hematologists, oncologists, transplant specialists, nurses, laboratory professionals and other healthcare specialists.

Treatment planning can integrate disease characteristics, previous therapy, stem cell availability, donor compatibility and overall health.

Cost & Price on Request

Price: Price on Request

The total cost of stem cell therapy depends on the underlying disease, treatment type and complexity of transplantation.

Potential costs may include:

• Specialist consultation

• Diagnostic testing

• Bone marrow testing

• Stem cell mobilization

• Stem cell collection

• Stem cell processing

• Donor evaluation

• Conditioning therapy

• Stem cell infusion

• Hospitalization

• Medications

• Blood transfusions

• Infection management

• GVHD management

• Follow-up testing

• Long-term follow-up care

A personalized cost estimate should be requested according to the patient's individual treatment plan.

Frequently Asked Questions

1. What conditions can stem cell therapy treat?

In cancer and hematology, stem cell therapy may be used for selected leukemias, lymphomas, multiple myeloma and certain bone marrow or blood disorders.

2. What is the difference between autologous and allogeneic stem cell therapy?

Autologous therapy uses the patient's own stem cells, while allogeneic therapy uses stem cells from a suitable donor.

3. How are stem cells collected?

Stem cells may be collected from the bloodstream through a specialized collection procedure, after appropriate preparation when required.

4. How long does recovery take after stem cell therapy?

Recovery varies according to the type of transplant, underlying disease, conditioning treatment, complications and immune recovery.

5. How much does stem cell therapy cost?

Price is available on request. The final cost depends on stem cell collection, conditioning treatment, transplantation, hospitalization, medications and follow-up care.

Product Details

Product Name: Stem Cell Therapy

Hospital: Cleveland Clinic

Brand: Cleveland Clinic

Country: United States

Specialty: Oncology & Cancer Care

Service Type: Stem Cell Therapy

Customer-Facing Price: Price on Request

International Patients: Available

Location: Cleveland, Ohio, USA