Stem Cell Transplant at Massachusetts General Hospital

Stem Cell Transplant is a specialized treatment that uses hematopoietic stem cells to restore blood-forming and immune-system function after intensive treatment for selected cancers and other serious blood or immune disorders. Depending on the condition, stem cells may come from the patient or a suitable donor.

Price

Price on Request

Why Price on Request?

The cost depends on the underlying disease, transplant type, stem-cell source, donor evaluation, conditioning treatment, hospitalization, medications and post-transplant monitoring. A personalized cost estimate can be provided after specialist assessment.

Complete Description

What Is Stem Cell Transplant?

A stem cell transplant replaces or restores blood-forming stem cells after intensive treatment.

It may involve:

• Autologous stem cell transplant

• Allogeneic stem cell transplant

• Donor stem cells

• Patient's own collected stem cells

The appropriate approach depends on the underlying disease and treatment plan.

Who May Need a Stem Cell Transplant?

Selected patients with conditions such as:

• Leukemia

• Lymphoma

• Multiple myeloma

• Myelodysplastic syndromes

• Certain bone marrow disorders

• Certain immune-system disorders

may be evaluated for stem cell transplantation.

Stem Cell Transplant Evaluation

Evaluation may include:

• Medical history

• Physical examination

• Blood testing

• Bone marrow examination

• Imaging when appropriate

• Disease-status assessment

• Organ-function testing

• Infection screening

Autologous Stem Cell Transplant

In an autologous transplant, the patient's own stem cells are collected and stored before intensive treatment.

The collected cells are subsequently returned to the patient.

Allogeneic Stem Cell Transplant

Allogeneic transplantation uses stem cells obtained from a suitable donor.

Donor evaluation may involve:

• HLA testing

• Blood testing

• Medical assessment

• Infectious disease screening

• Other compatibility assessments

Stem Cell Collection

Stem cells may be collected using specialized procedures appropriate to the patient's treatment plan.

The collection method depends on the source of the stem cells and the type of transplantation.

Conditioning Treatment

Some transplant protocols require conditioning before stem-cell infusion.

This may involve chemotherapy and, in selected cases, radiation therapy.

The intensity and type of conditioning depend on the disease and transplant approach.

Stem Cell Infusion

Following conditioning, the collected stem cells are administered through an intravenous infusion.

The transplanted cells can then begin establishing new blood-forming and immune-system cells.

Engraftment Monitoring

After transplantation, the medical team closely monitors the patient as the transplanted stem cells establish themselves.

Monitoring may include:

• Blood counts

• Infection surveillance

• Organ-function testing

• Medication monitoring

• Clinical assessment

Graft-versus-Host Disease Monitoring

Patients receiving allogeneic stem cells may be monitored for graft-versus-host disease (GVHD).

Specialist treatment and preventive strategies may be used when clinically appropriate.

Post-Transplant Care

Long-term follow-up may involve:

• Blood-count monitoring

• Infection prevention

• Medication management

• Disease surveillance

• Organ-function monitoring

• Management of transplant-related complications

Stem Cell Transplant Second Opinion

Patients may seek a stem cell transplant second opinion regarding:

• Transplant eligibility

• Autologous versus allogeneic transplantation

• Donor selection

• Conditioning treatment

• Transplant timing

• Previous treatment recommendations

Relevant medical records and pathology can be reviewed by specialists.

International Patient Stem Cell Transplant

International patients seeking stem cell transplantation in the United States should provide relevant medical documentation whenever available.

Useful records may include:

• Bone marrow biopsy reports

• Pathology results

• Blood tests

• Genetic or molecular testing

• Imaging

• Previous chemotherapy records

• Previous transplant evaluations

• Donor information when applicable

Complete documentation can help specialists determine the appropriate treatment pathway.

Benefits of Specialized Stem Cell Transplant Care

Specialized care may help:

• Assess transplant eligibility

• Determine the appropriate transplant type

• Evaluate potential donors

• Coordinate stem-cell collection

• Plan conditioning treatment

• Monitor engraftment

• Manage transplant complications

• Provide long-term follow-up

• Offer specialist second opinions

Why Choose Massachusetts General Hospital?

Massachusetts General Hospital provides specialized hematology, oncology and cellular therapy care in Boston, bringing together specialists experienced in the evaluation and treatment of complex blood and immune-system disorders.

Cost & Price on Request

Price: Price on Request

Potential costs may include:

• Hematology consultation

• Stem cell transplant evaluation

• Laboratory testing

• Bone marrow examination

• HLA and donor testing

• Stem-cell collection

• Conditioning treatment

• Stem cell transplant

• Hospitalization

• Medications

• Post-transplant monitoring

• Follow-up care

A personalized cost estimate can be requested following specialist assessment.

Frequently Asked Questions

1. What is a stem cell transplant?

A stem cell transplant uses blood-forming stem cells to restore the blood and immune system following intensive treatment for selected diseases.

2. What is the difference between autologous and allogeneic stem cell transplantation?

Autologous transplantation uses the patient's own collected stem cells, while allogeneic transplantation uses stem cells from a suitable donor.

3. Does stem cell transplantation require chemotherapy?

Some transplant protocols use chemotherapy or other conditioning treatment before the stem-cell infusion. The exact approach depends on the disease and treatment plan.

4. Can I get a stem cell transplant second opinion?

Yes. Patients may request specialist review of their diagnosis, previous treatment and proposed transplant plan, subject to hospital requirements.

5. Can international patients receive stem cell transplant care at Massachusetts General Hospital?

International patients may request evaluation and treatment subject to Massachusetts General Hospital's international patient processes, medical requirements and appointment availability.

Product Details

Product Name: Stem Cell Transplant

Hospital: Massachusetts General Hospital

Brand: Massachusetts General Hospital

Country: United States

Specialty: Transplant Medicine

Service Type: Stem Cell Transplant

Customer-Facing Price: Price on Request

International Patients: Subject to applicable eligibility and appointment requirements

Location: Boston, Massachusetts, United States