Bone Marrow Transplant at Massachusetts General Hospital

Bone Marrow Transplant is a specialized treatment that replaces damaged or diseased blood-forming cells with healthy hematopoietic stem cells. It may be considered for selected patients with certain blood cancers, bone marrow disorders and other serious blood or immune-system conditions.

Price

Price on Request

Why Price on Request?

The cost varies according to the underlying disease, transplant type, donor or stem-cell source, pre-transplant treatment, hospitalization, medications and post-transplant monitoring. A personalized cost estimate can be provided after specialist assessment.

Complete Description

What Is a Bone Marrow Transplant?

A bone marrow transplant replaces unhealthy or damaged blood-forming cells with healthy hematopoietic stem cells.

The stem cells may come from:

• A matched donor

• An alternative donor source

• The patient's own cells in selected treatment settings

Who May Need a Bone Marrow Transplant?

Selected patients with conditions such as:

• Leukemia

• Lymphoma

• Multiple myeloma

• Certain bone marrow disorders

• Certain immune-system disorders

• Other serious blood-related conditions

may be evaluated for transplantation.

Bone Marrow Transplant Evaluation

Before transplantation, patients may undergo:

• Medical history review

• Physical examination

• Blood testing

• Bone marrow examination

• Imaging when required

• Infection screening

• Organ-function assessment

• Disease-status evaluation

Autologous Transplant

In an autologous transplant, the patient's own stem cells are collected and later returned following appropriate treatment.

This approach may be used for selected diseases.

Allogeneic Transplant

An allogeneic transplant uses stem cells from another person who is medically suitable as a donor.

Donor selection may involve:

• HLA matching

• Blood testing

• Medical evaluation

• Infectious disease screening

Donor Evaluation

Potential donors undergo a separate medical assessment to determine whether donation is appropriate.

Evaluation may include:

• Medical history

• Physical examination

• Blood tests

• HLA testing

• Infectious disease screening

• Other donor-specific investigations

Conditioning Treatment

Some transplant protocols involve conditioning treatment before stem-cell infusion.

Conditioning may use chemotherapy and, in selected cases, radiation therapy to prepare the body for transplantation.

The treatment plan depends on the underlying disease and transplant approach.

Stem Cell Infusion

After the appropriate preparative treatment, healthy stem cells are administered through an intravenous infusion.

The transplanted cells can then begin the process of establishing new blood-forming cells.

Engraftment Monitoring

After transplantation, the medical team monitors the patient for engraftment, when transplanted stem cells begin producing new blood cells.

Monitoring may include:

• Blood counts

• Infection surveillance

• Organ-function testing

• Clinical assessment

Post-Transplant Care

Following transplantation, patients require close monitoring for:

• Infection

• Blood-count changes

• Medication effects

• Graft-related complications

• Organ complications

• Disease recurrence

Graft-versus-Host Disease Management

Patients receiving an allogeneic transplant may be monitored for graft-versus-host disease (GVHD).

The transplant team can provide preventive and therapeutic management when clinically necessary.

Bone Marrow Transplant Second Opinion

Patients may seek a bone marrow transplant second opinion regarding:

• Transplant eligibility

• Transplant timing

• Autologous versus allogeneic transplantation

• Donor selection

• Conditioning treatment

• Previous transplant recommendations

Relevant medical records, pathology and treatment history can be reviewed by specialists.

International Patient Bone Marrow Transplant

International patients seeking bone marrow transplantation in the United States should provide relevant medical documentation whenever available.

Useful records may include:

• Bone marrow biopsy reports

• Pathology results

• Blood test results

• Imaging

• Genetic or molecular testing

• Previous chemotherapy records

• Previous transplant evaluations

• Donor information when applicable

Complete documentation can help specialists determine the appropriate treatment pathway.

Benefits of Specialized Bone Marrow Transplant Care

Specialized transplant care may help:

• Assess transplant eligibility

• Determine the appropriate transplant approach

• Evaluate potential donors

• Coordinate conditioning treatment

• Provide stem-cell transplantation

• Monitor engraftment

• Manage transplant-related complications

• Provide long-term follow-up

• Offer transplant second opinions

Why Choose Massachusetts General Hospital?

Massachusetts General Hospital provides specialized hematology, oncology and cellular therapy care in Boston, bringing together specialists involved in the evaluation and treatment of complex blood and bone marrow disorders.

Cost & Price on Request

Price: Price on Request

Potential costs may include:

• Hematology consultation

• Transplant evaluation

• Laboratory testing

• Bone marrow examination

• HLA and donor testing

• Conditioning treatment

• Stem-cell collection

• Bone marrow transplant

• Hospitalization

• Medications

• Post-transplant monitoring

• Follow-up care

A personalized cost estimate can be requested following specialist assessment.

Frequently Asked Questions

1. What conditions can require a bone marrow transplant?

Selected blood cancers, bone marrow disorders and certain immune-system conditions may require evaluation for bone marrow or stem-cell transplantation.

2. What is the difference between autologous and allogeneic transplantation?

Autologous transplantation uses the patient's own collected stem cells, while allogeneic transplantation uses stem cells from a suitable donor.

3. Does every patient need a donor?

No. Autologous transplantation uses the patient's own stem cells. Allogeneic transplantation requires an appropriate donor or donor source.

4. Can I get a bone marrow transplant second opinion?

Yes. Patients may request specialist review of their diagnosis, previous treatment and transplant recommendations, subject to hospital requirements.

5. Can international patients receive bone marrow transplant care at Massachusetts General Hospital?

International patients may request evaluation and treatment subject to Massachusetts General Hospital's international patient processes, medical requirements and appointment availability.

Product Details

Product Name: Bone Marrow Transplant

Hospital: Massachusetts General Hospital

Brand: Massachusetts General Hospital

Country: United States

Specialty: Transplant Medicine

Service Type: Bone Marrow Transplant

Customer-Facing Price: Price on Request

International Patients: Subject to applicable eligibility and appointment requirements

Location: Boston, Massachusetts, United States